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CJC-1295 No DAC 5 mg

Also searched as: cjc 1295 no dac, mod grf 1-29

Sold as CJC-1295 No DAC - 5mg

$40 In stock

Strength
Ships from

For research use only. Not for human or veterinary use.

Ships from the USA or Canada. Shipping details

CJC-1295 No DAC, also called Mod GRF 1-29, is a synthetic 29-amino-acid peptide modeled on growth hormone-releasing hormone (GHRH), with four positions altered.19 It is designed to prompt the pituitary to release growth hormone, but FDA found no pharmacology studies of this form, and a 2026 review found no peer-reviewed human studies.19 Each vial holds 5 mg of freeze-dried powder.

Specifications

ClassGrowth hormone-releasing hormone (GHRH) analog; synthetic 29-amino-acid peptide1
Sequence (three-letter code)Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH212
Sequence (one-letter code)YaDAIFTQSYRKVLAQLSARKLLQDILSR-NH2 (29 residues; lowercase a marks D-alanine at position 2; C-terminal amide)1
Changes from natural GHRH(1-29)D-Ala2, Gln8, Ala15, Leu271
Molecular formulaC152H252N44O42 (free base)21
Molar mass3367.9 g/mol (PubChem); 3367.95 g/mol (FDA)21
CAS number446036-97-1 (free base, as listed by FDA); FDA identifies 863288-34-0 as a deleted CAS number13
PubChem CID91976842 (record titled CJC1295 Without DAC)2
FormFreeze-dried (lyophilized) powder
Vial contents5 mg per vial (the listing does not state the salt form)
Strength5 mg
Ships fromUSA, Canada
CategoriesAnti-Aging Peptides, Growth Hormone Peptides, Healing and Recovery Peptides, Muscle Growth Peptides
StorageVendor data relayed in FDA's 2024 review put the solid free base at 4 years or more at -20 °C and the acetate powder at up to 3 years.1 Neither figure was measured on this vial.

Bulk and wholesale orders

Labs that need CJC-1295 No DAC in bulk can apply for a wholesale account; terms are confirmed on application.

Questions about CJC-1295 No DAC

About CJC-1295 No DAC

CJC-1295 No DAC, also called Mod GRF 1-29, copies the first 29 amino acids of human growth hormone-releasing hormone (GHRH), the stretch that carries the hormone's full activity, and swaps four of them to slow breakdown.19 Without the swaps, the same 29 amino acids are sermorelin.149 GHRH tells pituitary cells to release growth hormone, which then raises IGF-1.19 The CJC-1295 name first belonged to a long-acting version with a drug affinity complex (DAC); the form without it appears to be first described in a 2010 report on a product seized in Norway.461

This page lists CJC-1295 No DAC for sale as a 5 mg research vial, with the CJC-1295 No DAC price and stock for each origin in the selector above. Before you buy CJC-1295 No DAC for a study, read What is CJC-1295 No DAC? for the safety record and regulatory history.

Research highlights

  • Related analog, 10 healthy men (1994): adding only the D-alanine swap at position 2 to GHRH(1-29) lengthened its disappearance half-time during IV infusion from 4.3 to 6.7 minutes.7
  • Seized product, Norway (2009): mass spectrometry found a 29-amino-acid peptide with a C-terminal amide whose sequence fit the peptide marketed as CJC-1295;6 FDA notes it had no DAC.1
  • Seized powders, Denmark (2019 report): some held analogs of modified GRF 1-29 with an extra glycine at the N-terminus.8 FDA cites it when warning of inconsistent CJC-1295 naming.1
  • The DAC form, healthy adults aged 21 to 61 (2006): one injection raised mean growth hormone 2 to 10 times for 6 days or more and IGF-1 1.5 to 3 times for 9 to 11 days; FDA says these results cannot be extrapolated to the form without DAC.51
  • Evidence grading (2026 review): the no-DAC form sits in tier D, the lowest, for having no peer-reviewed human studies; the DAC form is tier B and tesamorelin tier A.9

Regulatory status

No FDA-approved drug contains any form of CJC-1295, and FDA found none approved in 12 other countries or by the European Medicines Agency.1 On December 4, 2024, FDA's compounding advisory committee voted 13 to 0 against adding the free base, this peptide, to the 503A bulks list.10 FDA's safety-risk page places CJC-1295 among former category 2 substances withdrawn by their nominators, citing immunogenicity and serious adverse events such as increased heart rate and systemic vasodilatory reaction.11

In an August 2026 warning letter, FDA said research-use labels did not stop it treating an online seller's peptides as drugs for human use.12 WADA bans CJC-1295 at all times under S2.2.4.13

Handling and storage

Vendor data cited by FDA describe the free base as only slightly water-soluble but soluble in 1% acetic acid, and the acetate as soluble in water at 5 mg/mL.1 At that rate, 5 mg of the acetate needs at least 1 mL to dissolve fully. The listing does not name the salt form, so check the lot's certificate, if one is available, before choosing a diluent. The steps are in the reconstitution guide, and the reconstitution calculator works out the concentration.

Frequently asked questions

Which CJC-1295 No DAC strength is listed?

The listed strength is a 5 mg vial of freeze-dried powder; the selector shows its price and stock at each shipping origin. The same peptide is also one half of the CJC-1295 + Ipamorelin blend. The names Mod GRF 1-29 and CJC-1295 without DAC refer to this peptide, which FDA calls CJC-1295 (free base).91

Where does CJC-1295 No DAC ship from?

Orders ship from the USA and Canada to addresses across the United States. Stock is tracked for each origin, so the selector shows which one can send the vial before it goes in the cart. Delivery details are on the shipping page, and the rules for sending an order back are on Returns and refunds.

How should CJC-1295 No DAC be stored when it arrives?

The figures in FDA's review are vendor data for frozen storage: the free base solid stable for 4 or more years at -20 °C, the acetate powder up to 3 years at -20 °C and the acetate in solvent up to 1 year at -80 °C.1 FDA notes that peptides like this one can be extremely sensitive to heat, pH and concentration, which may make them clump or break down.1 Steps for sealed and mixed vials are in How to store peptides.

Is there a certificate of analysis for CJC-1295 No DAC?

Any certificates of analysis D2C Peptides can share are posted on the lab results page. The free base is C152H252N44O42, 3367.9 g/mol.2 The DAC form is heavier, at 3647.95 g/mol by FDA's figure.1 FDA also found that the research-use websites it checked did not name the form: free base, acetate or TFA.1

What supplies are used with a CJC-1295 No DAC vial?

Diluent and supplies are separate catalog items: bacteriostatic water, insulin syringes, a 3 mL Luer-Lok syringe, an 18G 1-inch needle and alcohol swabs. They are bench handling items, and nothing on this page is a direction for use in people.

Is this the same as CJC-1295 with DAC?

No. CJC-1295 with DAC is a separate vial. Its extra lysine carries a group that binds albumin in the blood: it was still in rat plasma after 72 hours, and its estimated half-life in healthy adults was 5.8 to 8.1 days.45 No human half-life is published for the no-DAC form.9 FDA treats the two as different active moieties that are not interchangeable.1

Written by D2C Peptides Editorial Team.

Pending qualified review.

Updated .

Sources

  1. FDA Briefing Document, Pharmacy Compounding Advisory Committee Meeting, December 4, 2024: CJC-1295-Related Bulk Drug Substances (FDA evaluation dated 11/15/2024). U.S. Food and Drug Administration, 2024.
  2. PubChem compound properties: CID 91976842 (CJC1295 Without DAC) and CID 56841945. PubChem, National Center for Biotechnology Information (NIH/NLM), 2026.
  3. PubChem synonyms for CID 56841945. PubChem, National Center for Biotechnology Information (NIH/NLM), 2026.
  4. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog (Jetté L et al.). Endocrinology, 2005.
  5. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults (Teichman SL et al.). Journal of Clinical Endocrinology and Metabolism, 2006.
  6. Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation (Henninge J et al.). Drug Testing and Analysis, 2010.
  7. Incorporation of D-Ala2 in growth hormone-releasing hormone-(1-29)-NH2 increases the half-life and decreases metabolic clearance in normal men (Soule S et al.). Journal of Clinical Endocrinology and Metabolism, 1994.
  8. Glycine-modified growth hormone secretagogues identified in seized doping material (Gajda PM et al.). Drug Testing and Analysis, 2019.
  9. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration (Dominikowski A et al.). Frontiers in Endocrinology, 2026.
  10. Final Summary Minutes of the Pharmacy Compounding Advisory Committee Meeting, December 4, 2024. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, 2024.
  11. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks (content current as of 04/22/2026). U.S. Food and Drug Administration, 2026.
  12. Warning Letter: NuScience Peptides LLC (MARCS-CMS 733652), August 24, 2026. U.S. Food and Drug Administration, 2026.
  13. World Anti-Doping Code International Standard: Prohibited List 2026. World Anti-Doping Agency (WADA), 2025.
  14. PubChem compound record: Sermorelin, Biologic Line Notation (sequence). PubChem, National Center for Biotechnology Information (NLM), 2026.