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D2C Peptides
Sermorelin vial

Sermorelin 10 mg

Sold as Sermorelin Peptide

$70 In stock

Strength

For research use only. Not for human or veterinary use.

Ships from the USA. Shipping details

Sermorelin is a synthetic peptide that matches the first 29 amino acids of human growth hormone-releasing hormone (GHRH), with an amidated end.1 It binds the GHRH receptor and prompts the pituitary gland to release growth hormone.222 This vial holds 10 mg of sermorelin as a freeze-dried powder for laboratory research. It is not currently FDA-approved: FDA withdrew its approvals for sermorelin (sold as Geref) in 2009.3

Specifications

ClassGrowth hormone-releasing hormone (GHRH) analog, GHRH(1-29)NH2113
SequenceYADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2 (29 amino acids, amidated end)4
Molecular formulaC149H246N44O42S5
Molar mass3357.9 g/mol5
CAS number86168-78-76
PubChem CID161324135
FormFreeze-dried (lyophilized) powder
Vial contents10 mg sermorelin per vial
Strength10 mg
Ships fromUSA
StorageIn 1991 FDA approved a 24-month shelf life for the Geref diagnostic powder (50 mcg per vial) stored at 7 C.7 That figure applies only to Geref; no independent stability data were found for this vial.

Supplies for Sermorelin

Bulk and wholesale orders

Labs that need a steady sermorelin supplier for larger quantities can apply for a wholesale account. Terms are confirmed on application.

Wholesale detailsApply for a wholesale account

Questions about Sermorelin

About Sermorelin

Natural GHRH (growth hormone-releasing hormone) has 44 amino acids, and sermorelin copies the first 29.1 That fragment is the shortest synthetic piece that keeps the hormone's full biological activity, and in human studies it stimulated growth hormone (GH) secretion from the anterior pituitary.13 It binds the GHRH receptor and mimics the natural hormone.2 The GH it raises comes from the body's own pituitary, so sermorelin is a releasing signal, not growth hormone itself.22

The sermorelin for sale here is a 10 mg vial of freeze-dried powder for laboratory research. For the full background, side effects and study doses, read What is Sermorelin?

Research highlights

These human studies are small: the largest treated 110 children.14

  • GH-deficient children: in a multicenter, open-label study, 110 previously untreated prepubertal children were treated for up to a year. In the 86 analyzed for efficacy, mean growth speed rose from 4.1 to 8.0 cm per year at 6 months.14
  • Compared with GH: in a randomized 6-month trial of 60 children with GH deficiency, GH produced faster growth (14.6 cm per year) than GHRH(1-29) given by continuous infusion (9.2 and 9.3 cm per year).15
  • Older men: in 10 healthy older men, 14 days on the higher of two doses raised 24-hour GH and IGF-1 until they no longer differed from those of 9 young men.16
  • Strength and body composition: in a 6-week study of 11 healthy men aged 64 to 76, with no control group, 2 of 6 strength measures and one endurance test improved, while weight and DEXA muscle and fat did not change.17
  • Short action: in 30 healthy men aged 19 to 43, the peptide was cleared quickly after an IV dose, but GH stayed raised for about 3 hours.18
  • Evidence quality: a 2026 review says benefits in healthy people remain uncertain because the human evidence is limited and largely indirect, and it notes that no long-term safety data exist.19

Regulatory status

FDA approved sermorelin acetate as Geref in 1990 as a diagnostic for testing the pituitary's GH release.203 A 1997 approval added a treatment for idiopathic GH deficiency in children with growth failure.83 The maker, EMD Serono, discontinued both products in 2008, and FDA withdrew both approvals effective June 18, 2009.3 In 2013 FDA determined that they were not withdrawn for reasons of safety or effectiveness.3 As of October 2026, Drugs@FDA lists both as discontinued with no label available, and DailyMed holds no sermorelin labels.8209

In a December 10, 2024 warning letter, FDA named an online seller's sermorelin among unapproved new drugs.10 It said labels reading "FOR RESEARCH USE ONLY" and "NOT INTENDED FOR HUMAN USE" did not change that, because the seller's website showed the products were intended for human use.10 Compounded sermorelin is not FDA-approved either.12 WADA's 2026 Prohibited List bans sermorelin at all times, in and out of competition.21

Handling and storage

The vial holds a dry powder that is dissolved in a diluent before lab use. If you buy sermorelin online for a lab, plan these separate items with it: Bacteriostatic Water, a 3mL Syringe, Luer-Lok Tip with an 18G 1-Inch Needle, Insulin Syringes (Pack of 10) and Alcohol Swabs (Pack of 2). The sermorelin price, $70, covers the vial alone.

No independent stability data were found for this vial, so general storage steps are in How to store peptides. Mixing steps, the supplies and the concentration math are in How to reconstitute Sermorelin. The reconstitution calculator and peptide calculator do the arithmetic. For more research compounds, see all peptides for sale.

Frequently asked questions

How much should sermorelin cost?

Here the 10 mg vial is listed from $70, and that covers the peptide only. Bacteriostatic water, syringes, needles and alcohol swabs are separate catalog items, each with its own page under Peptide supplies. The strength figure is the amount of peptide in the vial before any diluent is added. This page does not cover compounded prescription products.

Can I just buy sermorelin?

This vial is sold for laboratory research and labeled for research use only. Drugs@FDA lists both Geref products as discontinued and DailyMed holds no sermorelin labels, so no FDA-approved sermorelin appears to be marketed in the US.8209 In a December 2024 warning letter, FDA called one online seller's research-labeled sermorelin an unapproved new drug, because its website showed the products were meant for people.10 Section 503A pharmacy compounding must be based on valid patient-specific prescriptions, and compounded drugs are not FDA-approved.1112

How does the order ship, and what arrives?

Orders ship across the United States. Shipping options and times are kept on the Shipping page rather than repeated here. The vial arrives as a dry powder with no diluent inside, so plan the bacteriostatic water and syringes with the order. Published storage data cover only the approved Geref product, so this page makes no shelf-life claim for this vial.

Is there a certificate of analysis for this sermorelin?

Any certificates of analysis D2C Peptides can share are posted on the Lab results and certificates of analysis page. To ask about a specific lot before you order, use Contact us. This page states no purity figure, because no certificate for this product had been reviewed when it was written.

Written by D2C Peptides Editorial Team.

Pending qualified review.

Updated .

Sources

  1. PubChem Compound CID 16132413 (Sermorelin): record description from DrugBank. PubChem, NCBI, U.S. National Library of Medicine (source: DrugBank DB00010), 2026.
  2. PubChem Compound CID 16132413 (Sermorelin): mechanism of action. PubChem, NCBI, U.S. National Library of Medicine (source: DrugBank DB00010), 2026.
  3. Determination That GEREF (Sermorelin Acetate) Injection Products Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness (78 FR 14095, Docket FDA-2012-P-1071). U.S. Food and Drug Administration, Federal Register (GovInfo), 2013.
  4. PubChem Compound CID 16132413 (Sermorelin): biologic line notation. PubChem, NCBI, U.S. National Library of Medicine, 2026.
  5. PubChem Compound CID 16132413 (Sermorelin): computed properties. PubChem, NCBI, U.S. National Library of Medicine, 2026.
  6. PubChem Compound CID 16132413 (Sermorelin): CAS. PubChem, NCBI, U.S. National Library of Medicine, 2026.
  7. Approval Package for NDA 19-863/S001: Geref (sermorelin acetate for injection), approval letter and chemistry review. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, 1991.
  8. Drugs@FDA: GEREF, NDA 020443. U.S. Food and Drug Administration, 2026.
  9. DailyMed search results for sermorelin. U.S. National Library of Medicine (DailyMed), 2026.
  10. Warning Letter: Xcel Research LLC (MARCS-CMS 694608), December 10, 2024. U.S. Food and Drug Administration, 2024.
  11. Human Drug Compounding Laws. U.S. Food and Drug Administration, 2024.
  12. Compounding and the FDA: Questions and Answers. U.S. Food and Drug Administration, 2025.
  13. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency (Prakash and Goa), pharmacology. BioDrugs (PubMed abstract PMID 18031173, via NCBI E-utilities), 1999.
  14. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group (Thorner et al.). J Clin Endocrinol Metab (PubMed abstract PMID 8772599, via NCBI E-utilities), 1996.
  15. A comparative study of growth hormone (GH) and GH-releasing hormone(1-29)-NH2 for stimulation of growth in children with GH deficiency (Chen et al.), growth. Acta Paediatr Suppl (PubMed abstract PMID 8329830, via NCBI E-utilities), 1993.
  16. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men (Corpas et al.), results. J Clin Endocrinol Metab (PubMed abstract PMID 1379256, via NCBI E-utilities), 1992.
  17. Effects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly men (Vittone et al.), body composition and safety. Metabolism (PubMed abstract PMID 9005976, via NCBI E-utilities), 1997.
  18. Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration (Wilton et al.), intravenous. Acta Paediatr Suppl (PubMed abstract PMID 8329825, via NCBI E-utilities), 1993.
  19. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis (Dominikowski et al.), safety signals. Front Endocrinol (PMC full text PMC13322892), 2026.
  20. Drugs@FDA: GEREF, NDA 019863. U.S. Food and Drug Administration, 2026.
  21. The 2026 Prohibited List, World Anti-Doping Code (published in the Austrian Federal Law Gazette, BGBl. III Nr. 219/2025). World Anti-Doping Agency list, reproduced by the Austrian Federal Law Gazette (RIS), 2025.
  22. PubChem Compound CID 16132413 (Sermorelin): pharmacology. PubChem, NCBI, U.S. National Library of Medicine (source: DrugBank DB00010), 2026.
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