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GHRP-6 vial

GHRP-6 5 mg

Also searched as: ghrp 6, ghrp6

Sold as GHRP6 - 5mg

$30 In stock

Strength
Ships from

For research use only. Not for human or veterinary use.

Ships from the USA or Canada. Shipping details

GHRP-6 (growth hormone-releasing peptide-6) is a synthetic six-amino-acid peptide, first reported in 1984, that binds the ghrelin receptor and signals the pituitary to release growth hormone.47 This listing is a 5 mg vial of freeze-dried GHRP-6 for laboratory research. It has no approved label (DailyMed lists none), and FDA names it among compounding substances that may present significant safety risks.1617

Specifications

Also known asGrowth hormone-releasing peptide-6, GH-releasing hexapeptide 6, SK&F 110679, U-75799E2
ClassSynthetic hexapeptide of the GH-releasing peptide (GHRP) family; ghrelin receptor (GHS-R1a) agonist that also binds CD3647
Sequence (three-letter code)His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (D-tryptophan at position 2, D-phenylalanine at position 5, C-terminal amide)21
Molecular formulaC46H56N12O61
Molar mass873.0 g/mol1
CAS number87616-84-0 (PubChem also lists 145177-42-0, labeled free base)2
PubChem CID9919153 (CID 4345065, titled "Ghrp-6", has the same formula but no defined stereochemistry)13
FormWhite freeze-dried (lyophilized) solid
Salt formNot stated for this vial (PubChem lists both a free base and an acetate salt)2
Vial contents5 mg per vial
Strength5 mg
Ships fromUSA, Canada
CategoriesGrowth Hormone Peptides, Healing and Recovery Peptides, Muscle Growth Peptides
StorageGHRP-6 has no approved label, so no regulator-reviewed storage instructions exist; DailyMed lists none.16 Supplier data that FDA relayed in its review of a related peptide, ipamorelin, note that moisture cuts the long-term stability of freeze-dried peptides.23

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Questions about GHRP-6

About GHRP-6

GHRP-6 is a lab-made peptide of six amino acids, His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, with D-forms of tryptophan and phenylalanine at positions 2 and 5.21 The first report, in 1984, found it released growth hormone from incubated pituitary tissue and in live rats, monkeys, lambs and calves, with no rise in LH, FSH, TSH or prolactin.4 It predates the discovery of its target: the ghrelin receptor (GHS-R1a) was cloned in 1996, and its natural partner, the stomach hormone ghrelin, was identified in 1999.56 A second binding site, CD36, has been tied to cell-survival signaling in cell and animal work.7

Researchers looking for GHRP-6 for sale will find it here as a single 5 mg vial, and the selector above shows the GHRP-6 price and stock at each shipping origin. Side effects, study doses and the full source list are in What is GHRP-6?, worth reading before you buy GHRP-6 online for a project.

Research highlights

  • Healthy men (1989, 17 men): 30-minute IV infusions reliably raised growth hormone above a threshold dose, did not move LH, FSH, TSH or ACTH, and were well tolerated.8
  • Synergy (1990, 18 men): low IV doses acted synergistically with GHRH; prolactin and cortisol about doubled, but only at the highest dose tested.9
  • Dependence on GHRH (1998, 9 men): blocking the body's own GHRH cut the peak growth hormone rise from 33.8 to 6.2 µg/L.10
  • 34-hour infusion (1993, 9 young men): integrated growth hormone roughly doubled against saline and IGF-1 climbed from 252 to 312 µg/L, with no loss of pituitary response.11
  • Diagnosis (2000, 250 adults): given with GHRH as a single IV test, it separated adults with growth hormone deficiency from healthy adults at a 15 µg/L cut-off, and the hormone peaks caused no side effects.12
  • Sleep (1995, placebo-controlled, healthy men): four night-time IV doses lengthened stage 2 sleep (270 vs 245 minutes) without changing deep sleep, while raising ACTH and cortisol.13
  • Pigs (2007): in a heart attack model, damaged heart tissue weighed 78% less and the infarct was 50% thinner than with saline.14
  • Evidence level (2026 review): the human record is limited to phase I and small mechanistic studies; there are no controlled efficacy trials or long-term safety data.15

Regulatory status

GHRP-6 is not an FDA-approved drug, and DailyMed returned no label for it when searched on October 24, 2026.16 Since September 29, 2023, FDA has placed it in category 2 for outsourcing facilities (section 503B): bulk substances that may present significant safety risks.17 FDA cites a possible immune-reaction risk for certain routes, a potential effect on cortisol and higher blood sugar from reduced insulin sensitivity.17 For pharmacy compounding (section 503A), FDA's May 14, 2026 list puts GHRP-6 in category 3, substances nominated without adequate support.18 WADA bans it in and out of competition (class S2.2.4), and ClinicalTrials.gov lists no registered study.1920 Every vial is labeled: For research use only. Not for human or veterinary use.

Handling and storage

The vial holds freeze-dried powder of unstated salt form, and PubChem records GHRP-6 both as a free base and as an acetate.2 Independent stability data for GHRP-6 vials could not be found. FDA links the immune-reaction risk of compounded GHRP-6 to potential aggregation and peptide-related impurities.17 For lab work, see the reconstitution guide, and use the reconstitution calculator for the concentration math.

Frequently asked questions

Where does GHRP-6 ship from?

Orders ship from the USA and Canada to addresses across the United States. GHRP-6 has more than one listed shipping origin, and availability can differ between them, so check the selector at the top of this page for each origin's price and stock before checkout. The shipping page explains delivery options.

How should GHRP-6 be stored when it arrives?

No independent stability data for GHRP-6 vials were found, and there is no approved label to set storage rules.16 Keeping the powder dry matters, since moisture shortens the shelf life of freeze-dried peptides in supplier data relayed by FDA.23 Practical lab storage is covered in how to store peptides.

What strengths of GHRP-6 are available?

The vial on this page holds 5 mg. Two related ghrelin-receptor peptides are listed separately: GHRP-2, from the same GHRP family, and Ipamorelin. In pigs, GHRP-6 raised ACTH and cortisol, while ipamorelin did not raise them beyond what GHRH did, even at more than 200 times its effective dose.21

Is there a certificate of analysis for GHRP-6?

The lab results page lists certificates and other lab documents where available. An identity check should match PubChem's formula for GHRP-6, C46H56N12O6, and a molar mass of about 873 g/mol.1 Identity matters as much as purity: doping labs have found black-market products containing Gly-GHRP-6, the peptide with an extra glycine attached.22

What supplies are used with a GHRP-6 vial?

In the lab, the powder is dissolved in a sterile diluent such as bacteriostatic water, sold separately. Volumes are drawn with insulin syringes or a 3 mL Luer-Lok syringe and 18G needle, and stoppers are wiped with alcohol swabs. The reconstitution calculator does the concentration math. This is lab handling, not use in people.

Is GHRP-6 for human use?

No. GHRP-6 is supplied for laboratory research, with this label on every vial: For research use only. Not for human or veterinary use. It has no FDA-approved label and no registered clinical trial.1620 No country was found to have approved it as a medicine, and a 2017 review wrote that the GHRP family was still waiting for a clear clinical role.7

Written by D2C Peptides Editorial Team.

Pending qualified review.

Updated .

Sources

  1. PubChem compound CID 9919153 (Growth hormone releasing hexapeptide): computed properties. PubChem, National Library of Medicine (NIH), 2026.
  2. PubChem compound CID 9919153: synonyms. PubChem, National Library of Medicine (NIH), 2026.
  3. PubChem name lookup 'GHRP-6' (resolves to CID 4345065, Ghrp-6): computed properties. PubChem, National Library of Medicine (NIH), 2026.
  4. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone (Bowers CY et al.; PubMed abstract, PMID 6714155). Endocrinology (abstract via NCBI PubMed E-utilities), 1984.
  5. A receptor in pituitary and hypothalamus that functions in growth hormone release (Howard AD et al.; PMID 8688086). Science (abstract via NCBI PubMed E-utilities), 1996.
  6. Ghrelin is a growth-hormone-releasing acylated peptide from stomach (Kojima M et al.; PMID 10604470). Nature (abstract via NCBI PubMed E-utilities), 1999.
  7. Synthetic Growth Hormone-Releasing Peptides (GHRPs): A Historical Appraisal of the Evidences Supporting Their Cytoprotective Effects (Berlanga-Acosta J et al.; PMID 28469491, abstract). Clinical Medicine Insights: Cardiology (abstract via NCBI PubMed E-utilities), 2017.
  8. Effect of a new synthetic hexapeptide to selectively stimulate growth hormone release in healthy human subjects (Ilson BE et al.; PMID 2543692). Journal of Clinical Endocrinology and Metabolism (abstract via NCBI PubMed E-utilities), 1989.
  9. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone (Bowers CY et al.; PMID 2108187). Journal of Clinical Endocrinology and Metabolism (abstract via NCBI PubMed E-utilities), 1990.
  10. Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation (Pandya N et al.; PMID 9543138). Journal of Clinical Endocrinology and Metabolism (abstract via NCBI PubMed E-utilities), 1998.
  11. Effects of a prolonged growth hormone (GH)-releasing peptide infusion on pulsatile GH secretion in normal men (Jaffe CA et al.; PMID 7903313). Journal of Clinical Endocrinology and Metabolism (abstract via NCBI PubMed E-utilities), 1993.
  12. GH-releasing hormone and GH-releasing peptide-6 for diagnostic testing in GH-deficient adults (Popovic V et al.; PMID 11030292). The Lancet (abstract via NCBI PubMed E-utilities), 2000.
  13. Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man (Frieboes RM et al.; PMID 7617137). Neuroendocrinology (abstract via NCBI PubMed E-utilities), 1995.
  14. Growth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction (Berlanga J et al.; PMID 16989643). Clinical Science (abstract via NCBI PubMed E-utilities), 2007.
  15. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration (Dominikowski A et al.; full text). Frontiers in Endocrinology, 2026.
  16. DailyMed search results for 'GHRP-6'. DailyMed, National Library of Medicine (NIH), 2026.
  17. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks. U.S. Food and Drug Administration, 2026.
  18. Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act (updated May 14, 2026). US Food and Drug Administration, 2026.
  19. World Anti-Doping Code International Standard: Prohibited List 2026. World Anti-Doping Agency (official PDF, copy hosted by SEGAS, the Hellenic Athletics Federation), 2025.
  20. ClinicalTrials.gov API v2 study search: query term 'GHRP-6'. ClinicalTrials.gov, National Library of Medicine (NIH), 2026.
  21. Ipamorelin, the first selective growth hormone secretagogue (Raun K et al.; PMID 9849822). European Journal of Endocrinology (abstract via NCBI PubMed E-utilities), 1998.
  22. Analysis of new growth promoting black market products (Krug O et al.). Growth Hormone and IGF Research, 2018.
  23. FDA Briefing Document, Pharmacy Compounding Advisory Committee Meeting, October 29, 2024: Ipamorelin-Related Bulk Drug Substances (FDA evaluation dated 8/19/2024). U.S. Food and Drug Administration, 2024.
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