Selank 5 mg

About Selank

Selank is a heptapeptide, a chain of 7 amino acids, designed at the Institute of Molecular Genetics of the Russian Academy of Sciences with the V.V. Zakusov Research Institute of Pharmacology.⁵ It extends tuftsin (Thr-Lys-Pro-Arg), a fragment of the human immunoglobulin G heavy chain, with Pro-Gly-Pro to make the molecule more stable.⁵ Russia registers it as 0.15% nasal drops for adults with anxiety states.⁶ Here it is listed as a 5 mg research vial in the sleep and stress peptides range.

The human evidence is a handful of small Russian studies whose English abstracts omit doses, blinding and randomization.⁹¹⁰¹¹ A ClinicalTrials.gov search in October 2026 found no Selank trial.²⁵ Read What is Selank? for the mechanism research, side effects and full source list.

Research highlights

• Anxiety, 62 adults (2008): Selank and the benzodiazepine medazepam reduced anxiety to a similar degree, and Selank also showed anti-fatigue and stimulant effects.⁹
• Anxiety, 60 adults (2014): against phenazepam, Selank showed a pronounced anti-anxiety effect that lasted a week after the last dose.¹⁰
• Add-on use, 70 adults (2015): adding Selank to phenazepam brought an earlier response and fewer phenazepam side effects.¹¹
• Healthy volunteers (2020): in 52 adults split among Selank, Semax and placebo, brain scans 5 and 20 minutes after one injection showed altered links between the right amygdala and the right temporal cortex.¹²
• Human plasma, lab study (2001): Selank inhibited enkephalin-degrading enzymes (enkephalins are natural opioid peptides), with 50% inhibition at about 15 micromolar.¹³
• Rats (2022): one injection lowered a morphine-withdrawal score by 39.6%, close to the 49.3% seen with diazepam.¹⁴
• Rats (2010): a single injection during training kept the memory of a learned task more stable over 30 days.¹⁵

Regulatory status

Selank is not FDA-approved.⁸ FDA's list of compounding substances that may present significant safety risks shows selank acetate as a withdrawn nomination, warns of possible immune reactions from aggregation and impurities, and says FDA lacks important human safety information.¹⁶ A 2020 FDA warning letter said drugs a pharmacy compounded from Selank did not qualify for the compounding exemptions.¹⁷ Selank was not on the agenda when FDA's compounding advisory committee reviewed peptides in July 2026.¹⁸ WADA's 2026 Prohibited List does not name Selank, and reviews disagree on its status: a 2025 review rated it unclear, while a 2026 review says WADA prohibits it.²⁰²¹⁸ The List's class S0 bans substances not covered elsewhere that have no current government approval for human therapeutic use, and Russia has approved Selank.²⁰⁶

Handling and storage

No label or published study found gives mixing steps for Selank powder.⁶⁷ The Russian medicine needs none: it is a ready-made solution of 1.5 mg selank diacetate per mL with methylparaben as a preservative.⁷⁶ For freeze-dried peptides in general, Bachem advises against storing them in solution and suggests frozen aliquots when a solution must be kept.²² The reconstitution guide sets out the lab steps, and how to store peptides covers freezer and fridge storage.