Gonadorelin 2 mg

Sold as Gonadorelin Acetate - 2mg

$25 In stock

For research use only. Not for human or veterinary use.

Ships from the USA or Canada. Shipping details

Gonadorelin is synthetic GnRH: a 10-amino-acid peptide with the same sequence as the hypothalamic hormone that makes the pituitary release LH and FSH.¹² The vial is listed as 2 mg of gonadorelin acetate. Its clinical uses have included testing pituitary function and pulse therapy by infusion pump in hypothalamic amenorrhea.¹³¹⁷ Both FDA-approved human products are discontinued; the remaining FDA-approved gonadorelin products are cattle drugs.⁴⁵⁶

Specifications

Sequence (three-letter code)	pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2⁷⁸
Sequence (one-letter code)	XHWSYGLRPG, where X is pyroglutamic acid and the C-terminal glycine is amidated⁸
Length	10 amino acids (decapeptide)¹
Molecular formula	C55H75N17O13 (peptide); C57H79N17O15 (PubChem acetate record)⁹¹⁰
Molar mass	1182.3 g/mol (peptide); 1242.3 g/mol (PubChem acetate record)⁹¹⁰
CAS number	33515-09-2 (gonadorelin); 34973-08-5, 499785-55-6 and 52699-48-6 (gonadorelin acetate)¹¹¹²
PubChem CID	638793 (gonadorelin); 11980076 (gonadorelin acetate)⁹¹⁰
WHO ATC codes	H01CA01, V04CM01³
Vial contents	2 mg per vial, listed as gonadorelin acetate
Strength	2 mg
Ships from	USA, Canada
Category	Reproductive Health Peptides
Storage	No storage temperature is listed for this vial. For freeze-dried peptides, GenScript advises -20 °C away from bright light;²⁸ FDA-approved gonadorelin cattle solutions are labeled for 2 to 8 °C.¹³¹⁴

Supplies for Gonadorelin

Bulk and wholesale orders

Labs looking for a gonadorelin supplier for larger or repeat orders can open a wholesale application, and bulk terms are confirmed at that stage.

Wholesale details Apply for a wholesale account

Questions about Gonadorelin

What is Gonadorelin?

About Gonadorelin

DrugBank describes gonadorelin as GnRH made by solid-phase peptide synthesis, and states that it mainly stimulates the making and release of LH.¹³ Its initial half-life is 2 to 10 minutes, which DrugBank says requires infusion pumps for clinical use.³ Kisspeptin acts one step earlier in the same chain, by stimulating GnRH-driven hormone release, and is listed as Kisspeptin-10 in the Reproductive Health Peptides range.¹⁶

Gonadorelin for sale here is listed as a 2 mg vial of the acetate salt; the gonadorelin price and stock at each shipping origin are shown in the selector above. The clinical record and safety reports are on What is Gonadorelin?, worth reading before you buy gonadorelin for a study.

Research highlights

Ovulation, 1,002 women (meta-analysis of 35 studies, 2018): pulsed GnRH appeared to give high ovulation rates in hypothalamic amenorrhea, with similar rates under the skin and into a vein.¹⁷
Pregnancy against gonadotropins, 30 women (randomized trial, 2013): with hypothalamic amenorrhea plus PCOS, clinical pregnancy was 46% with pulsatile GnRH and 0% with FSH plus LH.¹⁸
Sperm production, 28 men with congenital hypogonadotropic hypogonadism (nonrandomized study, 2019): sperm appeared sooner with a gonadorelin pump than with cyclical gonadotropins (median 6 against 14 months); over 24 months, 90% of 10 and 83.3% of 18 men produced sperm, not a significant difference.¹⁹ Testosterone rose and stayed in the normal range in both groups.²⁰
Bone density, 22 young men (before-and-after study, 2015): spine and hip bone mineral density increased after 6 months of pulsatile gonadorelin in hypogonadotropic hypogonadism.²¹
Pituitary testing (records review, 234 girls, 2018): one IV dose of gonadorelin acetate served as a stimulation test in girls checked for early puberty, where a peak LH above 5.0 U/L counted as diagnostic.²²
Delivery pattern (animal study, rhesus monkeys with hypothalamic lesions, 1978): hourly GnRH pulses brought back pituitary hormone release, but a steady infusion could not sustain it.²³

Regulatory status

No FDA-approved gonadorelin product for human use is marketed in the US: Drugs@FDA lists Factrel (gonadorelin hydrochloride, approved 1982) and Lutrepulse Kit (gonadorelin acetate, approved 1989) as discontinued.⁴ FDA-approved gonadorelin animal drugs are cattle injectables that only a licensed veterinarian may use or order.⁵ FDA's 503B list places gonadorelin acetate in category 1, under evaluation, and gonadorelin is not on FDA's list of compounding substances that may present significant safety risks.²⁴²⁵ In a June 17, 2026 warning letter, FDA named a "Gonadorelin" sold online by Wholesale Peptide with "RESEARCH USE ONLY" labels as an unapproved new drug.²⁷ WADA's 2026 Prohibited List bans it at all times for male athletes, under S2.2.1.²⁶

Handling and storage

In a 1990 lab study, gonadorelin in water was most stable near pH 5.0.¹⁵ Acetate buffer favored stability, while phosphate buffer sped breakdown; a buffered formula (3% mannitol, 0.1 M acetate, pH 5.0) was predicted to lose 10% in 9.0 years at 20 °C.¹⁵ GenScript notes that peptides have a much shorter shelf life in solution than freeze-dried.²⁸ For mixing, the reconstitution guide sets out sterile lab steps, and the reconstitution calculator turns the vial amount and diluent volume into a concentration.

Frequently asked questions

Where does Gonadorelin ship from?

Gonadorelin ships from the USA and Canada to addresses across the United States. Stock is tracked separately for each origin, and the Ships from options above mark any origin that is out of stock before checkout. Delivery details are on the shipping page, and return terms are on the returns page.

How should Gonadorelin be stored when it arrives?

The listing gives no storage temperature; GenScript, a peptide maker, advises -20 °C away from bright light for freeze-dried peptides.²⁸ It lists tryptophan, which gonadorelin contains, as prone to oxidation, and histidine and arginine, also in its sequence, as prone to taking up moisture, so vials stay tightly capped.²⁸⁸ The refrigerated FDA-approved gonadorelin solutions are cattle drugs, not research vials.¹³¹⁴ More in how to store peptides.

What strength is the Gonadorelin vial?

The vial is listed as 2 mg, sold as gonadorelin acetate. The salt matters for concentration math: PubChem gives 1182.3 g/mol for the peptide and 1242.3 g/mol for its acetate record, so by those figures a given weight of the acetate holds about 5% less peptide.⁹¹⁰ Enter the vial amount and the diluent volume in the reconstitution calculator to get the concentration.

Is there a certificate of analysis for Gonadorelin?

Lab documents, where available, are on the lab results page. A certificate can be checked against PubChem's reference data, such as CAS 33515-09-2 and the formula C55H75N17O13 for the peptide.¹¹⁹ It is worth checking which tests it covers, such as identity, purity, peptide content, sterility and endotoxin.

What supplies are used with a Gonadorelin vial?

Five supplies are listed with this vial: bacteriostatic water, a 3 mL Luer-Lok syringe, an 18G 1-inch needle, insulin syringes and alcohol swabs. Bacteriostatic water is sterile water with 0.9% or 1.1% benzyl alcohol as a preservative.²⁹ GONAbreed, an FDA-approved gonadorelin solution for cattle, uses the same preservative: 10 mg per mL, beside 100 mcg of gonadorelin per mL.¹⁴ The supplies are listed for lab handling, not as directions for use in people.

Is Gonadorelin for human use?

No. It is sold for laboratory research only, and the listing carries this notice: For research use only. Not for human or veterinary use. FDA-approved gonadorelin cattle drugs are labeled not for people: GONAbreed reads 'Not for use in humans' and Zoetis Factrel reads 'Not for human use'.¹⁴¹³ WADA also bans gonadorelin for male athletes.²⁶

Written by D2C Peptides Editorial Team.

Pending qualified review.

Updated October 25, 2026.