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Peptide supplies explained

Bacteriostatic water, the most searched peptide supply, is sterile water with 0.9% or 1.1% benzyl alcohol added as a preservative, and its FDA-approved label limits it to diluting or dissolving drugs.1 It is one of the lab supplies, with syringes, needles and swabs, used to mix and measure a freeze-dried vial.

This page summarizes published sources for information only. It is not medical advice and does not tell anyone to use a product. Questions about your own health belong with a licensed clinician. For questions about an order or a product, contact us.

What is bacteriostatic water?

Bacteriostatic water is a sterile diluent: water for injection with benzyl alcohol added as a bacteriostatic preservative, at 0.9% (9 mg per mL) or, in a second Hospira version, 1.1% (11 mg per mL).1 It comes in a multiple-dose container, so repeated withdrawals can be made from one vial.1 It treats nothing. Its label describes it only as a diluent or solvent for drugs given intravenously, intramuscularly or subcutaneously.1 The vial we carry is on the Bacteriostatic Water for sale page.

The preservative limits the growth of bacteria that may enter a vial during repeated use.15 That protection has limits in time as well. FDA guidance gives an opened or needle-punctured multiple-dose container a 28-day beyond-use date unless the manufacturer's label states another, and CDC adds that the date never runs past the printed expiration date.56

FDA approved Hospira's Bacteriostatic Water for Injection on October 27, 1982 (NDA 018802), and lists its marketing status as prescription.2 FDA labels name bacteriostatic water as the diluent for approved hormone and peptide medicines, among them Egrifta WR (tesamorelin), whose kit includes its own 30 mL multiple-dose bottle,9 and Novarel (chorionic gonadotropin).10

Three label limits apply to any use. The label carries a boxed warning against use in newborns. Given into a vein without enough dissolved drug, it may cause hemolysis, the bursting of red blood cells. And some drugs are incompatible with a vehicle that contains benzyl alcohol.1 AmBisome, an antifungal, must be reconstituted with sterile water that has no bacteriostatic agent, because one may make it precipitate.11 For peptides in particular, a 2023 narrative review of protein and peptide medicines notes that some preservatives have been reported to increase particle formation, so a preservative has to suit the active ingredient.16

Vials sold next to research peptides sit in a different regulatory position from the approved product. In warning letters dated March 31 and August 24, 2026, FDA said bacteriostatic water offered alongside peptides that need reconstitution is intended for use with them by injection, which makes it a drug, and it called these products unapproved new drugs.131415 FDA said this held despite research-use and not-for-human-use statements on the sellers' labeling, citing evidence from their websites that the products were intended as drugs for human use.131415

Bacteriostatic water, sterile water and bacteriostatic saline

Three diluents with similar names do different jobs, and the label of the drug being mixed decides which one it takes.1

Bacteriostatic water Sterile water for injection Bacteriostatic saline
Preservative Benzyl alcohol, 0.9% or 1.1%1 None3 Benzyl alcohol, 0.9%4
Salt None; must be made near isotonic before use1 None3 Sodium chloride 9 mg per mL, isotonic4
Container Multiple-dose1 Single-dose only; unused portion discarded3 Multiple-dose4
Newborns Not for use (boxed warning)1 The labeled choice for preparing newborn medicines1 Not for use (boxed warning)4

Tesamorelin shows the difference in practice. EGRIFTA SV is mixed with sterile water and used right away, with leftover solution and diluent thrown out.36 EGRIFTA WR is mixed with bacteriostatic water, kept at room temperature and discarded 7 days after mixing.9 Not every bacteriostatic diluent uses benzyl alcohol, either: the 10 mg ZOMACTON (somatropin) vial comes with bacteriostatic water preserved with 0.33% metacresol.37

Insulin syringes and the units scale

Insulin syringes carry a fine needle of their own and are marked in insulin units rather than milliliters.22 Standard U-100 insulin holds 100 units per mL and most insulin syringes are marked for it, so on a U-100 syringe 1 unit is 0.01 mL.2019 The maker embecta offers 1 mL, 0.5 mL and 0.3 mL barrels that hold up to 100, 50 and 30 units, half-unit marks on the 0.3 mL size, and needles 6, 8 or 12.7 mm long. Concentrated U-500 insulin needs its own U-500 syringe.21

Needle length has its own evidence base for insulin. International expert recommendations published in 2016 call the shortest needles, including the 6 mm syringe needle, safe, effective and less painful as the first choice for all patient groups, and advise against intramuscular insulin injections because severe hypoglycemia may result.23

Because a unit mark is a volume, the amount of compound in it depends on the solution's concentration.19 The units converter switches between mL and U-100 units. The store's pack of 10 is on the Insulin Syringes for sale page.

The 3 mL Luer-Lok syringe

Federal rules define a piston syringe by three parts, a calibrated barrel, a plunger and a nozzle that takes a needle hub, and place it in Class II.24 Luer fittings join syringe and needle with either a push fit (a Luer slip) or a screw-in thread (a Luer lock), giving a secure, detachable, leak-proof connection.25 Luer-Lok is BD's name for its locking tip, and BD offers a 3 mL Luer-Lok syringe without a needle for general use.26 A 3 mL syringe holds the same volume as a 3 cc syringe, since 1 cc equals 1 mL.27 Next to a 1 mL insulin syringe, it holds three times as much, is read in mL and takes a separate needle. See the 3mL Syringe, Luer-Lok Tip for sale page.

Needle gauges: 18G, 23G and 25G

Each needle is a sharpened metal tube on a hub that attaches to the syringe, a Class II medical device under US rules.28 The gauge number rises as the needle gets thinner.22 BD color-codes its 1 inch PrecisionGlide hubs, pink for 18G, turquoise for 23G and blue for 25G.293031

CDC's vaccine tables show where each gauge sits in clinical practice. They list 22 to 25 gauge needles for intramuscular vaccines, 1 inch long for many adults, and 23 to 25 gauge needles 5/8 inch long for subcutaneous vaccines.32 By those tables, 23G and 25G fall inside both gauge ranges, with a length that matches the intramuscular rows, and 18G falls outside both. The tables describe vaccines given by clinicians, not any research compound. The supplier lists its 18G needle for drawing up and mixing rather than injecting.

The three needle pages: 18G 1-Inch Needle for sale, 23G x 1 Inch Needle for sale and 25G x 1 Inch Needle for sale.

Alcohol swabs

An alcohol swab, also called a prep pad, is a pad soaked in 70% isopropyl alcohol. The BD Alcohol Swabs label gives its purpose as antiseptic, lists preparing skin before an injection and decreasing germs in minor cuts and scrapes as its uses, and marks the pads flammable.33 They are regulated as over-the-counter drugs. In a 2017 final rule, though, FDA deferred deciding whether isopropyl alcohol is generally recognized as safe and effective for health care antiseptic use, pending more studies.3334

With vials, CDC's checklist calls for disinfecting the rubber septum with alcohol before each piercing.7 On skin before a prescribed injection, patient guides disagree. The MedlinePlus subcutaneous guide cleans the site with an alcohol pad,35 while the MedlinePlus insulin guide asks for clean, dry skin with no alcohol wipe at the site.20 The prescribed product's own instructions settle it. Swabs come in pairs on the Alcohol Swabs for sale page.

How the supplies fit together in the lab

Mixing a freeze-dried vial draws on most of these items in one sequence. The stopper is wiped with alcohol and left to dry,32 diluent is drawn up with a new needle and syringe and added to the vial, and every later entry uses a fresh needle and syringe, with no needle left in the stopper.76 The resulting strength equals the vial's contents divided by the diluent volume. Research peptides have no FDA label, so no mixing volume is established for them.1

The reconstitution guide gives the steps in order, the reconstitution calculator does the arithmetic, and the storage guide covers how mixed vials are kept.

Sharps disposal

FDA's method has two steps: put needles and syringes in a sharps disposal container right after use, then dispose of the container under your community's rules once it is about three-quarters full.38 FDA-cleared containers are rigid plastic with a fill line. When none is available, a heavy-duty plastic household container that stays upright, resists leaks and has a tight, puncture-resistant lid can stand in, labeled to warn of hazardous waste.3940 Loose needles never go in household trash, recycling or the toilet.41 Collection options vary by place, from drop boxes and supervised collection sites to household hazardous waste sites, mail-back programs and residential pick-up.38

The injection guide covers how prescribed injections are given and sharps disposal in more detail, and every item above is listed on the peptide supplies page.

Guides, tools and references

  • How to reconstitute a peptide vial

    Reconstituting a lyophilized peptide step by step: the supplies, the diluent, the math and storage after mixing.

  • Reconstitution calculator

    Enter the peptide amount and the diluent volume and get the concentration per mL and per syringe unit. Shows the formula. For reference only.

Frequently asked questions

Is bacteriostatic water just sterile water?

No. Sterile water for injection has no preservative and comes only in single-dose containers, so whatever is left after one use is discarded.3 Bacteriostatic water adds benzyl alcohol, which limits bacterial growth so a multiple-dose vial can be re-entered, generally for up to 28 days after first entry.15 The same preservative is why it is kept away from newborns and from drugs that need preservative-free water.111

Why is bacteriostatic water not used for newborns?

Because of its benzyl alcohol. A 1982 CDC report linked 16 deaths of preterm newborns at two US medical centers to benzyl alcohol in the solutions used to flush their catheters, at an estimated 99 to 405 mg/kg a day, with metabolic acidosis progressing to gasping breathing.8 Labels now carry a boxed warning against use in neonates and call for preservative-free sterile water when newborn medicines are prepared.1

Does the preservative make a vial germ-proof?

No. CDC says the preservative does nothing against viruses and cannot fully protect a vial from bacterial contamination.6 In two observational hospital studies, about 5% of opened vials grew microbes: 11 of 205 in Iran (2013) and 21 of 384 in Ethiopia (2023). In the Ethiopian study every contaminated sample came from a multiple-dose vial, and contamination was strongly linked to reused syringes or needles.1718

Has bacteriostatic water ever been recalled?

Yes. In September 2019 Hospira recalled one lot (W20308) of 30 mL Bacteriostatic Water for Injection vials nationwide, because sterilization could not be confirmed for some vials. The notice warned that vials without sterility assurance could cause serious infections, and Hospira said it had received no reports of such events.12

Are syringe units the same as milligrams?

No. A unit mark on a syringe is a volume: on a U-100 syringe, 1 unit is 0.01 mL.20 How many milligrams that volume holds depends on the concentration of the solution. FDA has warned that confusion between units, milligrams and milliliters may have contributed to overdoses of 5 to 20 times the intended amount when people drew compounded semaglutide from vials.19

Written by D2C Peptides Editorial Team.

Pending qualified review.

Updated .

Sources

  1. Bacteriostatic Water for Injection, USP (benzyl alcohol 0.9% and 1.1%), prescribing information, Hospira (revised 08/2019; same label text as the current DailyMed SPL). Hospira, Inc. (Pfizer), official labeling site labeling.pfizer.com, 2019.
  2. Drugs@FDA: Bacteriostatic Water for Injection in Plastic Container, NDA 018802 (Hospira), product overview. U.S. Food and Drug Administration (Drugs@FDA), 2026.
  3. Sterile Water for Injection, USP (single-dose, preservative-free), prescribing information, Hospira (revised 3/2025). Hospira, Inc. (Pfizer), official labeling site labeling.pfizer.com, 2025.
  4. Bacteriostatic 0.9% Sodium Chloride Injection, USP, prescribing information, Hospira (revised 02/2019). Hospira, Inc. (Pfizer), official labeling site labeling.pfizer.com, 2019.
  5. Selection of the Appropriate Package Type Terms and Recommendations for Labeling Injectable Medical Products Packaged in Multiple-Dose, Single-Dose, and Single-Patient-Use Containers for Human Use: Guidance for Industry. U.S. Food and Drug Administration (CDER, CBER, CDRH, Office of Combination Products), 2018.
  6. Preventing Unsafe Injection Practices (Injection Safety, information for healthcare providers). U.S. Centers for Disease Control and Prevention (CDC), 2024.
  7. Injection Safety Checklist (subset of the CDC Infection Prevention Checklist for Outpatient Settings), CDC-INFO Pub ID 221176. U.S. Centers for Disease Control and Prevention and the Safe Injection Practices Coalition (CDC Stacks), 2012.
  8. Neonatal Deaths Associated With Use Of Benzyl Alcohol: United States. MMWR 1982;31(22):290-1 (June 11, 1982). U.S. Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, 1982.
  9. EGRIFTA WR (tesamorelin) for injection, prescribing information and patient instructions (revised 3/2025). U.S. Food and Drug Administration (Drugs@FDA label; Theratechnologies Inc.), 2025.
  10. Novarel (Chorionic Gonadotropin for Injection, USP) label, FDA-hosted 2011 version (BLA 017016, supplement 156; FDA notes it may not be the latest label). U.S. Food and Drug Administration (Drugs@FDA label; Ferring Pharmaceuticals), 2011.
  11. AMBISOME (amphotericin B) liposome for injection, prescribing information (Drugs@FDA label dated 11/04/2024, NDA 050740). U.S. Food and Drug Administration (Drugs@FDA label; Astellas), 2024.
  12. Hospira, Inc., Issues A Voluntary Nationwide Recall for one lot of Bacteriostatic Water for Injection, USP, due to a Potential Lack of Sterility Assurance (company announcement, September 6, 2019). U.S. Food and Drug Administration (Recalls, Market Withdrawals and Safety Alerts), 2019.
  13. Warning Letter 721806: Gram Peptides (March 31, 2026). U.S. Food and Drug Administration, CDER Office of Unapproved Drugs and Labeling Compliance, 2026.
  14. Warning Letter 721088: Lovega LLC dba Pink Pony Peptides (March 31, 2026). U.S. Food and Drug Administration, CDER Office of Unapproved Drugs and Labeling Compliance, 2026.
  15. Warning Letter 735067: TXP Innovations LLC dba Tex Peptides (August 24, 2026). U.S. Food and Drug Administration, CDER Office of Unapproved Drugs and Labeling Compliance, 2026.
  16. Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview (Stroppel L, et al.; PMID 36839885; doi 10.3390/pharmaceutics15020563). Pharmaceutics (record via Europe PMC), 2023.
  17. Microbial contamination of single- and multiple-dose vials after opening in a pulmonary teaching hospital (Baniasadi S, et al.; PMID 23294643; doi 10.1016/j.bjid.2012.09.005). Brazilian Journal of Infectious Diseases (record via Europe PMC), 2013.
  18. Bacterial contamination of single and multiple-dose parenteral injection vials after opening and antibiotic susceptibility of isolates at Jimma Medical Center, Jimma, Southwest Ethiopia (Tabor A, et al.; PMID 37457638; doi 10.1016/j.infpip.2023.100290). Infection Prevention in Practice (record via Europe PMC), 2023.
  19. FDA alerts health care providers, compounders and patients of dosing errors associated with compounded injectable semaglutide products. U.S. Food and Drug Administration, 2024.
  20. Giving an insulin injection. MedlinePlus Medical Encyclopedia, U.S. National Library of Medicine, 2024.
  21. Ultra-Fine Insulin Syringes. embecta (Embecta Corp.), 2026.
  22. Needle Technology for Insulin Administration: A Century of Innovation (Heinemann L et al.). Journal of Diabetes Science and Technology, 2023.
  23. New Insulin Delivery Recommendations (Frid AH et al.). Mayo Clinic Proceedings, 2016.
  24. 21 CFR 880.5860 Piston syringe (2025 edition). U.S. Government Publishing Office (Code of Federal Regulations), 2025.
  25. Safety Considerations to Mitigate the Risks of Misconnections with Small-bore Connectors Intended for Enteral Applications (guidance for industry and FDA staff). U.S. Food and Drug Administration, 2015.
  26. 3 mL BD Luer-Lok Syringe only (catalog 309657). Becton, Dickinson and Company (BD), 2026.
  27. Drawing medicine out of a vial. MedlinePlus Medical Encyclopedia, U.S. National Library of Medicine, 2026.
  28. 21 CFR 880.5570 Hypodermic single lumen needle (2025 edition). U.S. Government Publishing Office (Code of Federal Regulations), 2025.
  29. 18 G x 1 in BD PrecisionGlide Needle (catalog 305195). Becton, Dickinson and Company (BD), 2026.
  30. 23 G x 1 in. BD PrecisionGlide Needle (catalog 305145). Becton, Dickinson and Company (BD), 2026.
  31. 25 G x 1 in. BD PrecisionGlide Needle (catalog 305125). Becton, Dickinson and Company (BD), 2026.
  32. Chapter 6: Vaccine Administration (Pink Book). U.S. Centers for Disease Control and Prevention.
  33. ISOPROPYL ALCOHOL swab (BD Alcohol Swabs) label. U.S. National Library of Medicine, DailyMed (labeler: Becton Dickinson and Company), 2024.
  34. Safety and Effectiveness of Health Care Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use (final rule). Federal Register (U.S. Food and Drug Administration), 2017.
  35. Subcutaneous (SQ) injections. MedlinePlus Medical Encyclopedia, U.S. National Library of Medicine, 2025.
  36. EGRIFTA SV (tesamorelin for injection) prescribing information and instructions for use. U.S. Food and Drug Administration (Drugs@FDA label), 2024.
  37. ZOMACTON (somatropin) for injection, prescribing information (revised 7/2025). DailyMed, U.S. National Library of Medicine, 2025.
  38. Best Way to Get Rid of Used Needles and Other Sharps. U.S. Food and Drug Administration, 2023.
  39. Sharps Disposal Containers. US Food and Drug Administration, 2021.
  40. Safely Using Sharps (Needles and Syringes) at Home, at Work and on Travel. U.S. Food and Drug Administration, 2021.
  41. DOs and DON'Ts of Proper Sharps Disposal. U.S. Food and Drug Administration, 2021.